Onglyza, Kombiglyze: Heart Failure, Pancreatic Cancer, Thyroid Cancer Investigation

Manufactured by AstraZeneca and Bristol-Myers Squibb, Onglyza (saxagliptin) and Kombiglyze XR (saxagliptin and metformin HCI extended-release) Type 2 diabetes medications are facing a rising number of lawsuits nationwide. Onglyza and Kombiglyze belong to a group of Type 2 diabetes medications called DPP-4 inhibitors and victims throughout the United States have sparked safety concerns regarding potential health problems associated with these medications such as heart failure, pancreatic cancer and thyroid cancer. Victims claim that the manufacturers of such drugs failed to warn the general public regarding the risk of developing severe heath injuries while under medication.

In April 2015, the FDA ordered Onglyza to carry a warning regarding the increased risk of heart failure since data from most recent studies show that Onglyza had greater risks of heart failure hospitalizations reported. Onglyza became a famous drug because compared with other diabetes medications, it does not encourage weight gain as it effectively controls blood sugar. In November 2011, Onglyza added information about pancreatitis in its warnings and precautions. Pancreatitis may lead to pancreatic cancer, a type of cancer that is complicated to cure because it can only be diagnosed in later stages. Since Kombiglyze XR is a combination of metformin and the active ingredient of Onglyza, this drug carries the same risks as Onglyza along with added possible complications from metformin. Victoza (liraglutide) is a similar medication as Kombiglyze and studies show that Victoza caused malignant thyroid tumors at clinically appropriate dosages thus, raising a concern regarding the possible link between thyroid cancer and Kombiglyze. Both linked to life-threatening side effects, Onglyza and Kombiglyze XR has been associated with increased risk of heart failure as well as a higher-than-normal risk of thyroid and pancreatic cancer.

Most common Onglyza and Kombiglyze XR side effects include:

  • Swelling or fluid retention
  • Nausea
  • Fatigue
  • Headaches
  • Urinary tract infections
  • Upper respiratory tract infections
  • Severe and persistent joint pain
  • Development of pre-cancerous cells
  • Difficulty breathing or swallowing

People who have suffered complications after taking Onglyza or Kombiglyze XR allege that the manufacturer continued to market their products despite having knowledge of the possible dangers, negligently and fraudulently marketed their medication, failed to run sufficient pre-market trials and failed to adequately warn both patients and health care providers regarding the possible side effects of their products. If you or anyone you know suffered from heart failure or pancreatitis or was diagnosed with thyroid or pancreatic cancer after taking Onglyza or Kombiglyze XR, Please Contact Us and provide any details along with contact information. If you prefer to leave a voicemail you can call 1.858.236.9020. GetClassActionMoney.com can then forward these requests to our network of attorneys that may contact you if a Class Action Lawsuit is to be pursued.